If you are looking for portability and modern capabilities, relying on a 2010 desktop application may no longer be your best path forward. Microsoft has shifted modern customization to the cloud:

Does not interfere with newer versions of SharePoint Designer (2013) installed on the same machine.

Microsoft SharePoint Designer 2010 (SPD 2010) is a specialized freeware tool for creating and modifying Microsoft SharePoint sites, workflows, and web pages. It is the successor to SharePoint Designer 2007 and was released to the web on April 21, 2010. As a key component of the Microsoft SharePoint family, it empowers advanced users and developers to rapidly build SharePoint solutions in response to business needs.

If you are trying to resolve a specific issue with a SharePoint deployment, let me know:

: Even if you require a "portable" solution to avoid administrative restrictions, the application requires deep hooks into the operating system's DLLcap D cap L cap L